That's ignition timing, the previous conversation has been referring to the engines crank-timing.

Raising the compression will raise power across the performance curve, low and high rpm, since HP is a proportional to compression. You have to correct the plug temperature (timing) for it to be fully effective, if your plug setup is out of range, the full potential will not be achieved.

Any highly tuned/modified engine will require a finer tune or setup. That's why low performance engines operate flawlessly no matter what plug, fuel, you use, and throughout a huge temp range. When you try to extract all the power an engine is capable of producing, the engine "gets" VERY intolerant to miss tune/setup.