How big is the track you will be running on? I would start with a 16 or a 17 and see how it does. The 17 might be a little to much punch. I am running a 1400kv on 6S and I am running a 16t which puts me at 31080rpm and a top speed of 43.75.

With your same setup using the 2200kv and 4s you would be at 32560rpm and 45.84 top speed with a 16t pinion.

I am running on a medium sized outdoor track with a pretty long straight and the motor pulls the whole way down the straight and never tops out.