I had to do a quick break in a couple weeks ago. Idled one tank through it at 200-240ish and then ran 3 tanks through it doing small runs varying throttle input as much as possible. Threw it on the track for 2 rich practice sessions and then raced it. Tune still changed a bit each qualifier and engine temps dropped each run as well.
Raced it again the following weekend. It now has 1/2 gallon on it and has had a "race tune" for most of that. Couldnt tell you how long it will last but it runs great.