I would highly recommend the Hotwire interface. It allows you to upgrade the ESC with new firmware which Tekin seems to be popping out beta releases every few months that improve performance. The latest, 194, makes the motor run cooler while using the same settings, and improves 4 cell performance.
It also allows you to put it in Sensored only mode for 10.5 and higher motors which is the way to go and i don't believe can be done using the MODE button.
Get one you will be amazed at how much it gets used.