If you figure out some way to run a front rib/rear fuzzy or a slick setup, yeah, probably. Slashes aren't like traditional stadium trucks where you want the tires to hold like a Formula 1 car, there's only so much the chassis can take before it goes over.
A little over a week ago I went to an indoor dirt track, and even with a worn-out set of the stock tires it was still pretty easy to get the truck up on 2 wheels if I wasn't careful. I couldn't imagine putting a set of fuzzies or slicks on one of these things and being able to drive it.