Your radio has the ability to reverse the direction that a channel operates. For steering, this could be used to correct if the car was turning left when you turned the wheel to the right.
When an ESC is struggling to calibrate, reversing the throttle channel of your radio can sometimes help.
Go the REV menu and reverse channel 2 if it is currently set to 'NOR', set it to 'REV'. If currently set to 'REV', then set it to 'NOR'. Recalibrate the ESC after doing this. Be extra sure that checked the trims and sub trims of channel 2 and that they are at 0.