You're probably sick of me replying David, but I'll go again anyway
Start with 25/96 gearing with 45mm tyres and a 3.5t. Play with boost and turbo as you go to get the speed with good temperatures and run time (start low).
Get some Ulti J soft rears and J medium fronts. They work really nice. Trinity Red Dot additive.
Protoform AMR12 body works, but the Strakka or TR12 also seem to work OK. I tried the BMR12, and while it looks sweet, I preferred the AMR.
1/12 on a big track like Brendale shouldn't be much fun - but it is!!