That's a loaded question lol but basically when I'm setting up my 1/12th I start with tire size. Get them where you like it dependant on the track
I run mine 45mm rears 43mm fronts. Next set your ride height for our bumpy track it 4mm all around
rear track width I go with about 180mm (use shims and also make sure both sides are even
front Toe I set next to around zero to neg 1 degree (out)
Now I get the camber to around -1 degree
Set tweak next (with out damper tubes installed)
Other settings you may want to play with
Damper tube oil weight
center spring oil and tension