I did that before using academy truck wheels or traxxas rear wheels, worked well to monster around, you just need to pay attention to the gearing. I would say if this is something you like, pickup a larger spur from mrc (I think the 74 tooth is the biggest that will fit, call and confirm).
It is also possible to see about doing a full truck conversion as well, Dave G did a concept of one on a thread here, generated lots of interest using parts from the gas truck on the V2 Pro.
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